Saturday, 4 January 2014

Breast Cancer Risk are more in Black women as compare to White women !




A study of breast cancer patients aged 40 and under found that just 71 per cent of black women survived for five years after diagnosis, compared with 82 per cent of white women.

Some of the difference could be explained by the fact that black patients had larger and more aggressive tumours on average, and were at greater risk of "triple negative" cancer which does not respond to hormone therapy. But these factors alone did not account for the sizeable difference between ethnic groups despite each having the same access to health care, the study of 2,915 women found.

It suggests that other factors, which could include biological differences, a lower awareness of symptoms or even cultural differences, could be contributing to the problem. For example, language barriers could prevent recent immigrants from accessing health care, they suggested, while some research suggests black women are less likely to self-check for lumps than other ethnic groups.

The study confirmed previous research that showed that black women tend to have more aggressive tumours. It also found that breast cancer was more likely to reoccur in black women. In general, young black women had poorer relapse-free survival compared with young white women, even after the researchers adjusted their findings for factors such as body mass index, tumour size and whether the cancer had spread to the lymph nodes.

There were no significant differences in overall survival or breast cancer reoccurrence between white and Black women. Further research is needed to understand why black women had poorer outcomes, and what can be done to improve their chances. The researchers speculate that there could be both genetic and social factors involved, citing, for example, that immigrant women may be less likely to register with a GP.

This study has found that young black women had poorer five-year overall survival and relapse-free survival than young white women. Outcomes remained worse even after factors which could potentially influence the results were taken into account.There were no significant differences in overall survival or breast cancer reoccurrence between women of white and Asian ethnicity.
This study compared outcomes of different ethnic groups in an age group that is not eligible for breast screening and in a population that receives entirely public-funded healthcare, thus eliminating a number of potential confounding socio-economic factors. However, although the proportion of black patients in the cohort is similar to the English population as a whole, the cohort only contained a small number of black and Asian women.

Further research will be required to determine why these black women may have had poorer outcomes, and whether steps can be taken to improve cancer outcomes for black women.



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Wednesday, 1 January 2014

What happens after treatment for breast cancer?


Treatment for Breast Cancer

For many women with breast cancer, treatment may remove or destroy the cancer. Completing treatment can be both stressful and exciting. You may be relieved to finish treatment, but find it hard not to worry about cancer coming back. This is a very common concern in people who have had cancer.
It may take a while before your fears lessen. But it may help to know that many cancer survivors have learned to live with this uncertainty and are leading full lives. For other people, the cancer may never go away completely. These people may get regular treatments with chemotherapy, radiation therapy, or other treatments to try to help keep the cancer in check. Learning to live with cancer that does not go away can be difficult and very stressful. It has its own type of uncertainty.


When treatment ends, your doctors will still want to watch you closely. It is very important to go to all of your follow-up appointments. During these visits, your doctors will ask questions about any problems you may have and may do exams and lab tests or x-rays and scans to look for signs of cancer or treatment side effects.
Almost any cancer treatment can have side effects. Some may last for a few weeks to months, but others can last the rest of your life. This is the time for you to talk to your cancer care team about any changes or problems you notice and any questions or concerns you have.
At first, your follow-up appointments will probably be scheduled for every 3 to 6 months. The longer you have been free of cancer, the less often the appointments are needed. After 5 years, they are typically done about once a year. If you had breast-conserving surgery, you will get a mammogram about 6 months after surgery and radiation are completed, and then at least every year. Women who had a mastectomy should continue to have yearly mammograms on the remaining breast.
You should have pelvic exams every year because these drugs can increase your risk of uterine cancer. This risk is highest in women who have gone through menopause. Be sure to tell your doctor right away about any abnormal vaginal bleeding, such as vaginal bleeding or spotting after menopause, bleeding or spotting between periods, or a change in your periods. Although this is usually caused by a non-cancerous condition, it can also be the first sign of uterine cancer.
Other tests such as blood tumor marker studies, blood tests of liver function, CTs, bone scans, and chest x-rays are not a standard part of follow-up. Getting these tests won’t help a woman treated with breast cancer live longer. They will be done (as indicated) if you have symptoms or physical exam findings that suggest that the cancer has recurred. These and other tests may be done as part of evaluating new treatments by clinical trials.
If symptoms, exams, or tests suggest a recurrence, imaging tests such as an x-ray, CT scan, PET scan, MRI scan, bone scan, and/or a biopsy may be done. Your doctor may also measure levels of blood tumor markers such as CA-15-3, CA 27-29, or CEA. The blood levels of these substances go up in some women if their cancer has spread to bones or other organs such as the liver. They are not elevated in all women with recurrence, so they aren't always helpful. If they are elevated, your doctor might use them to monitor the results of therapy.
If cancer does recur, your treatment will depend on the location of the cancer and what treatments you've had before. It may mean surgery, radiation therapy, hormone therapy, chemotherapy, targeted therapy, or some combination of these. For more information on how recurrent cancer is treated

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